European shares test two-year highs, yen volatile before BOJ

LONDON (Reuters) - European shares inched towards two-year highs and German Bunds dipped on Monday, as a political attempt to break a budget impasse in the United States and expectations of aggressive Japanese stimulus bolstered the appetite for shares.


U.S. House Republican leaders said on Friday they would seek to pass a three-month extension of federal borrowing authority in the coming days to buy time for the Democrat-controlled Senate to pass a plan to shrink budget deficits.


European shares <.fteu3> were supported by the news <.eu>, but with no clear response from the Democrats and a thin session expected due to a market holiday in the United States, the impact on assets such as bonds and commodities was limited.


By 1400 GMT London's FTSE 100 <.ftse>, Paris's CAC-40 <.fchi> and Frankfurt's DAX <.gdaxi> were up 0.3 to 0.4 percent, leaving the pan-European FTSEurofirst 300 within touching distance of a two-year high and MSCI's world index <.miwd00000pus> steady at a 20-month high. <.l><.eu/>


Expectations that the Bank of Japan will deliver a bold monetary easing plan at the end of its two-day meeting on Tuesday also supported shares and created choppy conditions in the currency market.


According to sources familiar with the BoJ's thinking, the government of new Prime Minister Shinzo Abe and the central bank have agreed to set 2 percent inflation as a new target, supplanting a softer 1 percent 'goal'.


The yen, which has fallen 13 percent against the dollar over the last two months as the shift in Japanese policy has taken shape, touched a new 2-1/2 year low in early trading but then firmed as traders cut short positions given the BOJ has often fallen short of market expectations.


"Investors are being mindful that the moves we have seen over the course of the last month or two are just worth locking in at least until we understand how the BOJ are really going to play in the future," said Jeremy Stretch, head of currency strategy at CIBC World Markets.


CURRENCY WARS


Japanese equities have surged in recent weeks in anticipation of a more aggressive monetary policy stance, but not everyone is happy.


The slump in the yen has prompted Russia's deputy central bank governor to warn of a new round of 'currency wars' and the medium-term risk of running ultra-loose monetary policies is likely to be a theme of the World Economic Forum in Davos, which opens on Wednesday.


With little in the way of economic data or debt issuance and U.S. markets shut for the Martin Luther King public holiday, the rest of the day was expected to be a fairly quite for investors.


Ahead of the first European finance ministers' meeting of the year, most euro zone government bonds were trading virtually flat and the euro was steady at $1.3316.


Market pressure on Europe is now less intense thanks to the European Central Bank's promise to prevent a collapse of the euro. Policymakers are set to discuss Cyprus's plight and plans for the euro zone's bailout fund to directly recapitalize banks.


"Negotiations will be complex, and a final decision is unlikely to emerge soon. Risks for sovereign spreads in the periphery should be limited, but we have some concerns that the long-term solution may fall short of what a real banking union needs," said UniCredit economist Marco Valli.


POLITICAL GAME


The efforts by Republican lawmakers to give the U.S. government leeway to pay its bills for another three months dented demand for safe haven assets and pushed German government bond yields near the top of this year's range.


The U.S. Treasury needs congressional authorization to raise the current $16.4 trillion limit on U.S. debt sometime between mid-February and early March. A failure to achieve that could lead to a debt default.


"This is part of the political game, it remains to be seen whether the Democrats will accept it," KBC strategist Piet Lammens said, adding that investors' working scenario was that a solution to raise the ceiling would be eventually found anyway.


One of the key factors that drove 2-year German yields higher last week was also the prospect of sizeable early repayments of the 1 trillion euros euro zone banks took from the ECB roughly a year ago.


The central bank will publish on Friday how much banks plan to return at the optional first repayment date on January 30. A Reuters poll on Monday showed around 100 billion euros are expected to be repaid although some predict it could be as high as 250 billion.


OIL OVERSUPPLY


German markets showed no reaction after the country's centre-left opposition party edged Chancellor Angela Merkel's conservatives from power in a regional election on Sunday, reviving its flagging hopes for September's national election.


Oil prices took their cues from a report in the United States at the end of last week that showed consumer sentiment at its weakest in a year as a result of the uncertainty surrounding the country's debt crisis.


Concerns about demand overshadowed supply disruption fears reinforced by the Islamist militant attack and hostage-taking at a gas plant in Algeria, a member of the Organization of Petroleum Exporting Countries.


Brent futures were down by 40 cents to $111.47 per barrel by mid-afternoon. U.S. crude shed 43 cents to $95.13 per barrel after touching a four-month high last week.


"The over-riding fundamental feeling in the market is that crude oil is over-supplied in 2013," said Tony Nunan, an oil risk manager at Mitsubishi.


Last week's data showing a pick-up in the Chinese economy helped keep growth-sensitive copper prices steady at roughly $8,056 an ounce. Gold, meanwhile, reversed Friday's losses to stand at $1,688 an ounce.


(Additional reporting by Sudip Kar-Gupta, Marious Zaharia and Anooja Debnath; Editing by Peter Graff)



Read More..

Algeria expects heavy hostage toll as West defends ally


ALGIERS/IN AMENAS, Algeria (Reuters) - Algeria said on Sunday it expected heavy hostage casualties after its troops ended a desert siege, but Western governments warned against criticizing tactics used by their vital ally in the struggle with Islamists across the Sahara.


An Algerian minister acknowledged the death toll would rise, and a private television station reported that 25 bodies had been found at the gas plant near the town of In Amenas after forces staged a final assault against the Islamist hostage-takers on Saturday.


Some Western governments had expressed frustration at not being informed of the Algerian authorities' plans to storm the complex. But France, which is fighting Islamist rebels across the desert in Mali, joined Britain in playing down any suggestion the response from Algeria - the main military power in the Sahara region - had been over-hasty or heavy-handed.


"What everyone needs to know is that these terrorists who attacked this gas plant are killers who pillage, rape, plunder and kill. The situation was unbearable," French Foreign Minister Laurent Fabius said.


"It's easy to say that this or that should have been done. The Algerian authorities took a decision and the toll is very high but I am a bit bothered ... when the impression is given that the Algerians are open to question. They had to deal with terrorists," he told Europe 1 radio in an interview.


The Islamists' pre-dawn attack on Wednesday has tested Algeria's relations with the outside world, exposed the vulnerability of multinational oil operations in the Sahara and pushed Islamist radicalism in northern Africa to centre stage.


Algeria, scarred by a civil war with Islamist insurgents in the 1990s which claimed 200,000 lives, had insisted there would be no negotiation in the face of terrorism.


Prime Minister David Cameron pointed out on Sunday its record in fighting Islamists. "Of course people will ask questions about the Algerian response to these events, but I would just say that the responsibility for these deaths lies squarely with the terrorists who launched this vicious and cowardly attack," he said in a television statement.


"We should recognize all that the Algerians have done to work with us and to help and coordinate with us. I'd like to thank them for that. We should also recognize that the Algerians too have seen lives lost among their soldiers."


France especially needs close cooperation from Algeria to have a chance of crushing Islamist rebels in northern Mali. Algiers has promised to shut its porous 1,000-km border with Mali to prevent al Qaeda-linked insurgents simply melting away into its empty desert expanses and rugged mountains.


Algeria's permission for France to use its airspace, confirmed by Fabius last week, also makes it much easier to establish direct supply lines for its troops which are trying to stop the Islamist rebels from taking the whole of Mali.


HIGHER DEATH TOLL


Algeria's Interior Ministry had reported on Saturday that 23 hostages and 32 militants were killed during the assaults launched by Algerian special forces to end the crisis, with 107 foreign hostages and 685 Algerian hostages freed.


However, Minister of Communication Mohamed Said said this would rise when final numbers were issued in the next few hours. "I am afraid unfortunately to say that the death toll will go up," Said was quoted as saying by the official APS news agency.


Details are only slowly emerging on what happened during the siege, which marked a serious escalation of unrest in northwestern Africa.


Private Algerian television station Ennahar said on Sunday that 25 bodies had been discovered at the Tiguentourine plant, adding that the operation to clear the base would last 48 hours.


The bodies were believed to belong to hostages executed by the militants, said Ennahar TV, which is known to have good sources within Algerian security.


In London, Cameron said three British nationals had been confirmed killed, while a further three Britons plus a British resident were also believed to be dead.


One Briton had already was confirmed killed when the gunmen seized the hostages at the plant near the Libyan border, run by Norway's Statoil along with Britain's BP and Algeria's state oil company.


MULTINATIONAL HOSTAGE-TAKERS


Said reported that the militants had six different nationalities and the operation to clear the plant of mines laid by the hostage-takers was still under way.


Believed to be among the 32 dead militants was their leader, Abdul Rahman al-Nigeri, a Nigerien close to al Qaeda-linked commander Mokhtar Belmokhtar, presumed mastermind of the raid.


One American has also been confirmed dead. Statoil said five of its workers, all Norwegian nationals, were still missing. Japanese and American workers are also unaccounted for.


On Saturday President Barack Obama said the United States was seeking a "fuller understanding" from Algerian authorities of what had happened, but added that "the blame for this tragedy rests with the terrorists who carried it out".


BP's chief executive Bob Dudley said on Saturday four of its 18 workers at the site were missing. The remaining 14 were safe.


The militant attack was one of the most audacious in recent years and almost certainly planned before French troops launched the operation in Mali this month to stem an advance by Islamist fighters.


Hundreds of hostages escaped on Thursday when the army launched a rescue operation, but many hostages were killed.


Before the Interior Ministry released its provisional death toll, an Algerian security source said eight Algerians and at least seven foreigners were among the victims, including two Japanese, two Britons and a French national.


The U.S. State Department said on Friday one American, Frederick Buttaccio, had died but gave no further details.


Mauritanian news agencies identified the field commander of the group that attacked the plant as Nigeri, a fighter from one of the Arab tribes in Niger who had joined the Algerian Salafist Group for Preaching and Combat (GSPC) in early-2005.


That group eventually joined up with al Qaeda to become Al Qaeda in the Islamic Maghreb (AQIM). It and allied groups are the targets of the French military operation in Mali.


The news agencies described him as "one of the closest people" to Belmokhtar, who fought in Afghanistan and then in Algeria's civil war of the 1990s. Nigeri was known as a man for "difficult missions", having carried out attacks in Mauritania, Mali and Niger.


The apparent ease with which the fighters swooped in from the dunes to take control of an important energy facility, which produces some 10 percent of the natural gas on which Algeria depends for its export income, has raised questions over the country's outwardly tough security measures.


Algerian officials said the attackers may have had inside help from among the hundreds of Algerians employed at the site.


Security in the half-dozen countries around the Sahara desert has long been a preoccupation of the West. Smugglers and militants have earned millions in ransom from kidnappings.


The most powerful Islamist groups operating in the Sahara were severely weakened by Algeria's secularist military in the civil war in the 1990s. But in the past two years the regional wing of al Qaeda gained fighters and arms as a result of the civil war in Libya, when arsenals were looted from Muammar Gaddafi's army.


(Additional reporting by Balazs Koranyi in Oslo, Estelle Shirbon and David Alexander in London, Brian Love in Paris, Daniel Flynn in Dakar; Writing by David Stamp; Editing by Alison Williams)



Read More..

Why does Michelle Obama need two Twitter accounts?






Michelle Obama is on Twitter! That was big news on Thursday, the first lady’s birthday. The White House announced that Mrs. Obama had launched a new Twitter account, @FLOTUS, and lots of folks chimed in with messages welcoming her to the world of micro-blogging social media.


But hold it – wasn’t she already on Twitter? We’ve been following @MichelleObama since the beginning of the 2012 presidential campaign. Is this a reboot, a dual account, or what? Is it the equivalent of the grand opening of a store that’s been in business for months?






Sort of, yes. Except it’s a retail establishment that has two branches kept separate for legal reasons.


RECOMMENDED: Michelle Obama: 10 quotes on her birthday


The invaluable Mashable has the full story here. The @MichelleObama feed is paid for and run by the Obama/Biden political campaign machinery. That’s why it was so active during the summer and fall, as it exhorted everybody to get out and vote, and in general pushed the fortunes of the incumbent presidential ticket. It’s an overtly political use of social media.


The first lady’s Pinterest site is run the same way. Most of those photos of her and her family, and favorite recipes (grilled peaches with yogurt and pistachios?), and exhortations about “why we vote” were put up by campaign staff.


Mrs. Obama’s new @FLOTUS handle reflects her official White House duties, however. It’s run by people from her office who are executive branch (and hence official US government) employees.


Legally speaking, @FLOTUS tweets will have to be stuff that deals with her official duties and the nation as a whole, as opposed to President Obama’s political fortunes. Thus on Thursday she tweeted “Join me and Barack for #MLK Day of Service” after thanking everyone for sending birthday wishes.


Get our FREE 2013 Global Security Forecast now


Hmm. @FLOTUS has sent three tweets, and it’s got more than 78,000 followers. That’s a pretty good tweet-to-listener ratio.


Most of this social media stuff is done by staff, of course. The few that she sends herself are supposed to be signed “-mo.”


Is the White House actually good at social media? We think that question can be answered definitively only by someone more versed in the dark electronic arts than we are. But from our point of view, it’s a pretty shrewd operator. Take the White House petition site. You can put up a petition on anything, and if it reaches a certain signature level in a certain period of time, the White House will respond with its point of view.


Most of the coverage of this “We the People” effort has focused on the weird stuff: petitions for Texas to secede, to deport CNN’s Piers Morgan, and so forth. And responding to them has to be a pain for staff. Mother Jones has a piece on Friday in which anonymous staffers gripe about having to spend time actually writing about why the US won’t build a Death Star, and things like that.


But to us, “We the People” really is a clever technique for harvesting e-mail addresses. When creating an account to sign stuff, you can check whether you want to receive missives from the White House. Most of the petitions are in fact about real policy – the need for more or less gun control, for instance. What the White House may get out of this is a continually growing list of voter contact information segmented by policy interest. To push the president’s new gun policies, for instance, they may send targeted e-mails to pro-control addresses, urging them to contact Congress.


We think this because media organizations do the same thing with interactive questionnaires and quizzes. We figure out who’s interested in what kind of stories and we direct those subjects their way.


Surprised? Don’t be. Building brand loyalty – everybody’s got whole new ways of approaching this old problem in today’s Internet age.


RECOMMENDED: Betty Ford to Michelle Obama: How seven first ladies have changed the office


Related stories


Read this story at csmonitor.com


Become a part of the Monitor community


Social Media News Headlines – Yahoo! News





Title Post: Why does Michelle Obama need two Twitter accounts?
Url Post: http://www.news.fluser.com/why-does-michelle-obama-need-two-twitter-accounts/
Link To Post : Why does Michelle Obama need two Twitter accounts?
Rating:
100%

based on 99998 ratings.
5 user reviews.
Author: Fluser SeoLink
Thanks for visiting the blog, If any criticism and suggestions please leave a comment




Read More..

Jennifer Lawrence Trashes Her Oscar Rivals - for Laughs









01/20/2013 at 08:45 AM EST







Jason Sudeikis and Jennifer Lawrence



How to get the jump on your sister Oscar nominees? Host Saturday Night Live – and come out punching.

That was Jennifer Lawrence's modus operandi this weekend, with the Silver Linings Playbook's Best Actress contender taking good-natured swipes at her competition during her silver-tongued opening monologue on the NBC comedy show.

About Jessica Chastain, she said: "In Zero Dark Thirty you caught Bin Laden. So what? In Winter's Bone I caught a squirrel, and then ate it."

Naomi Watts: You were in The Impossible. You know what else is impossible? You beating me on Oscar night."

Quvenzhané Wallis, the 9-year-old nominee for Beasts of the Southern Wild: "You think you can beat me? [In best Gary Coleman voice] 'What you talkin' 'bout, Wallis?' Also, the Alphabet called. It wants its letters back."

And Emmanuelle Riva, from the French film Amour: "An 85-year-old French lady. Um, yeah, I think I can take you."

Also in line for ribbing by the rest of the cast on the show, which featured The Lumineers as the musical guests, were disgraced athlete Lance Armstrong (played by Jason Sudeikis), reputed hoax victim Manti Te'o (Bobby Moynahan), outspoken Golden Globes honoree Jodie Foster (Kate McKinnon) and the scowling, Globes party-pooper Tommy Lee Jones (Bill Hader).

Though not personally at the end of a satirical sharp stick, Lawrence did tip her hat to her Hunger Games persona Katniss Everdeen by participating in a mock Post-Hunger Games press conference.

The running gag was how could Katniss go for Peeta (played by Taran Killam) because he's so short. The gamers were also asked if they used performance-enhancing drugs.

To see if Lawrence does topple the other actresses ... the 85th annual Academy Awards will air live on Sunday, Feb. 24, on ABC from the Dolby Theatre in Hollywood.

Read More..

Wall Street Week Ahead: Earnings, money flows to push stocks higher

NEW YORK (Reuters) - With earnings momentum on the rise, the S&P 500 seems to have few hurdles ahead as it continues to power higher, its all-time high a not-so-distant goal.


The U.S. equity benchmark closed the week at a fresh five-year high on strong housing and labor market data and a string of earnings that beat lowered expectations.


Sector indexes in transportation <.djt>, banks <.bkx> and housing <.hgx> this week hit historic or multiyear highs as well.


Michael Yoshikami, chief executive at Destination Wealth Management in Walnut Creek, California, said the key earnings to watch for next week will come from cyclical companies. United Technologies reports on Wednesday while Honeywell is due to report Friday.


"Those kind of numbers will tell you the trajectory the economy is taking," Yoshikami said.


Major technology companies also report next week, but the bar for the sector has been lowered even further.


Chipmakers like Advanced Micro Devices , which is due Tuesday, are expected to underperform as PC sales shrink. AMD shares fell more than 10 percent Friday after disappointing results from its larger competitor, Intel . Still, a chipmaker sector index <.sox> posted its highest weekly close since last April.


Following a recent underperformance, an upside surprise from Apple on Wednesday could trigger a return to the stock from many investors who had abandoned ship.


Other major companies reporting next week include Google , IBM , Johnson & Johnson and DuPont on Tuesday, Microsoft and 3M on Thursday and Procter & Gamble on Friday.


CASH POURING IN, HOUSING DATA COULD HELP


Perhaps the strongest support for equities will come from the flow of cash from fixed income funds to stocks.


The recent piling into stock funds -- $11.3 billion in the past two weeks, the most since 2000 -- indicates a riskier approach to investing from retail investors looking for yield.


"From a yield perspective, a lot of stocks still yield a great deal of money and so it is very easy to see why money is pouring into the stock market," said Stephen Massocca, managing director at Wedbush Morgan in San Francisco.


"You are just not going to see people put a lot of money to work in a 10-year Treasury that yields 1.8 percent."


Housing stocks <.hgx>, already at a 5-1/2 year high, could get a further bump next week as investors eye data expected to support the market's perception that housing is the sluggish U.S. economy's bright spot.


Home resales are expected to have risen 0.6 percent in December, data is expected to show on Tuesday. Pending home sales contracts, which lead actual sales by a month or two, hit a 2-1/2 year high in November.


The new home sales report on Friday is expected to show a 2.1 percent increase.


The federal debt ceiling negotiations, a nagging worry for investors, seemed to be stuck on the back burner after House Republicans signaled they might support a short-term extension.


Equity markets, which tumbled in 2011 after the last round of talks pushed the United States close to a default, seem not to care much this time around.


The CBOE volatility index <.vix>, a gauge of market anxiety, closed Friday at its lowest since April 2007.


"I think the market is getting somewhat desensitized from political drama given, this seems to be happening over and over," said Destination Wealth Management's Yoshikami.


"It's something to keep in mind, but I don't think it's what you want to base your investing decisions on."


(Reporting by Rodrigo Campos, additional reporting by Chuck Mikolajczak and Caroline Valetkevitch; Editing by Kenneth Barry)



Read More..

Algerian army stages "final assault" on gas plant


ALGIERS/IN AMENAS, Algeria (Reuters) - The Algerian army on Saturday carried out a "final assault" on al Qaeda-linked gunmen holed up in a desert gas plant, killing 11 of the Islamists after they took the lives of seven foreign hostages.


"It is over now, the assault is over, and the military are inside the plant clearing it of mines," a local source familiar with the operation told Reuters.


The state oil and gas company, Sonatrach, said the militants who attacked the plant on Wednesday and took a large number of hostages had booby-trapped the gas complex with explosives.


The exact death toll among the gunmen and the foreign and Algerian workers at the plant near the town of In Amenas close to the Libyan border remained unclear.


Earlier on Saturday, Algerian special forces found 15 burned bodies at the plant. Efforts were underway to identify the bodies, the source told Reuters, and it was not clear how they had died.


Sixteen foreign hostages were freed on Saturday, a source close to the crisis said. They included two Americans, two Germans and one Portuguese.


Britain said fewer than 10 of its nationals at the plant were unaccounted for.


The attack on the plant swiftly turned into the biggest international hostage crises in decades, pushing Saharan militancy to the top of the global agenda.


Reports earlier put the number of hostages killed at between 12 to 30, with many foreigners still unaccounted for, among them Norwegians, Japanese, Britons and Americans.


The U.S. State Department said on Friday one American, Frederick Buttaccio, had died but gave no further details. The French defense minister said he understood there were no more French workers among the hostages.


Two Norwegians were released overnight, leaving six unaccounted for, while Romania said three of its nationals had been freed. A number of Japanese engineering workers were still unaccounted for.


Scores of Westerners and hundreds of Algerian workers were inside the heavily fortified compound when it was seized before dawn on Wednesday by Islamist fighters who said they wanted a halt to a French military operation in neighboring Mali.


Hundreds escaped on Thursday when the army launched its operation, but many hostages were killed.


(Additional reporting by Ali Abdelatti in Cairo, Eamonn Mallie in Belfast, Gwladys Fouche in Oslo, Mohammed Abbas in London, Padraic Halpin and Conor Humphries in Dublin, Andrew Quinn and David Alexander in Washington, Brian Love in Paris; Writing by Giles Elgood; Editing by Sonya Hepinstall)



Read More..

Thank You to the OpenStack Members Who Voted in the Individual Director Election






HP Cloud Services would like to thank all of the OpenStack® Foundation member/electors who participated in the recent Individual Director election.


The OpenStack Foundation regularly conducts elections for Individual Directors of the Foundation’s Board.  This process is very important for the legitimacy of the Foundation and for the health of the project. These directors represent the voices and interests of the developers and contributors to the OpenStack project as a whole, and of the operators of OpenStack-based clouds. Read more about Thank You to the OpenStack Members Who Voted in the Individual Director Election »






Linux/Open Source News Headlines – Yahoo! News




Read More..

Nicole Richie Sets Yet Another Trend - But What Is It?




Style News Now





01/18/2013 at 06:30 PM ET



Trend ReportJason Merritt/Getty; Sara De Boer/Startracks; Steve Granitz/WireImage


Three shows down, and a lot more to go! So far, we’ve spotted tons of great trends at the Golden Globe Awards, Critics’ Choice Awards and People’s Choice Awards, however, three have totally stood out to us — two because they’re so rampant, and one because it’s so unusual. Let’s break it down:



Up: 50 shades of blue. From powder to navy, the red carpet has been a sea of oceanic shades so far. On the lighter end of the color spectrum recently were Nicole Richie in a periwinkle Naeem Khan gown, Jessica Chastain in a seafoam Calvin Klein Collection number and Lucy Liu in a sky-blue floral-print creation. Ladies like Amanda Seyfried, Emmy Rossum and Amy Adams, however, slipped into deep, midnight hues. Who’s got dibs on baby and royal blue? We think we’ll find out soon.




Down: Red lips. Surprisingly, Julianna Margulies was one of the few stars sporting a classic cherry pout on the red carpet this week — most celebs went for nudes, pinks and dark, vampy shades. Expect to see more bold beauty choices — like Jessica Alba’s juicy citrus lip, Kaley Cuoco’s plum pout and Julianne Moore’s funky fuchsia smile — throughout the rest of awards season.



Up: Thigh-high slits. Sorry, Angelina: Eva Longoria and other daring stars are stealing your right leg’s thunder. Though Longoria earned the title of “Most Gam-Baring Gown” the night of the Globes, she saw some stiff competition from Lea Michele, Miranda Kerr, Halle Berry, Katharine McPhee and Claire Danes — all of whom showed off their never-ending stems in super-sexy designs. Can the hemlines possibly get higher for next week’s Screen Actors Guild Awards? They just might!


For more on up-and-coming trends, check out our thoughts on floral print, red accessories and sexy minis.


Tell us: Which trends are you excited to see more of on the red carpet this awards season? Vote in our poll below! 






–Jennifer Cress


PHOTOS: SEE OUR FAVORITE DRESSES OF AWARDS SEASON — SO FAR!


Read More..

Lilly drug chosen for Alzheimer's prevention study


Researchers have chosen an experimental drug by Eli Lilly & Co. for a large federally funded study testing whether it's possible to prevent Alzheimer's disease in older people at high risk of developing it.


The drug, called solanezumab (sol-ah-NAYZ-uh-mab), is designed to bind to and help clear the sticky deposits that clog patients' brains.


Earlier studies found it did not help people with moderate to severe Alzheimer's but it showed some promise against milder disease. Researchers think it might work better if given before symptoms start.


"The hope is we can catch people before they decline," which can come 10 years or more after plaques first show up in the brain, said Dr. Reisa Sperling, director of the Alzheimer's center at Brigham and Women's Hospital in Boston.


She will help lead the new study, which will involve 1,000 people ages 70 to 85 whose brain scans show plaque buildup but who do not yet have any symptoms of dementia. They will get monthly infusions of solanezumab or a dummy drug for three years. The main goal will be slowing the rate of cognitive decline. The study will be done at 50 sites in the U.S. and possibly more in Canada, Australia and Europe, Sperling said.


In October, researchers said combined results from two studies of solanezumab suggested it might modestly slow mental decline, especially in patients with mild disease. Taken separately, the studies missed their main goals of significantly slowing the mind-robbing disease or improving activities of daily living.


Those results were not considered good enough to win the drug approval. So in December, Lilly said it would start another large study of it this year to try to confirm the hopeful results seen patients with mild disease. That is separate from the federal study Sperling will head.


About 35 million people worldwide have dementia, and Alzheimer's is the most common type. In the U.S., about 5 million have Alzheimer's. Current medicines such as Aricept and Namenda just temporarily ease symptoms. There is no known cure.


___


Online:


Alzheimer's info: http://www.alzheimers.gov


Alzheimer's Association: http://www.alz.org


___


Follow Marilynn Marchione's coverage at http://twitter.com/MMarchioneAP


Read More..

Wall Street Week Ahead: Earnings, money flows to push stocks higher

NEW YORK (Reuters) - With earnings momentum on the rise, the S&P 500 seems to have few hurdles ahead as it continues to power higher, its all-time high a not-so-distant goal.


The U.S. equity benchmark closed the week at a fresh five-year high on strong housing and labor market data and a string of earnings that beat lowered expectations.


Sector indexes in transportation <.djt>, banks <.bkx> and housing <.hgx> this week hit historic or multiyear highs as well.


Michael Yoshikami, chief executive at Destination Wealth Management in Walnut Creek, California, said the key earnings to watch for next week will come from cyclical companies. United Technologies reports on Wednesday while Honeywell is due to report Friday.


"Those kind of numbers will tell you the trajectory the economy is taking," Yoshikami said.


Major technology companies also report next week, but the bar for the sector has been lowered even further.


Chipmakers like Advanced Micro Devices , which is due Tuesday, are expected to underperform as PC sales shrink. AMD shares fell more than 10 percent Friday after disappointing results from its larger competitor, Intel . Still, a chipmaker sector index <.sox> posted its highest weekly close since last April.


Following a recent underperformance, an upside surprise from Apple on Wednesday could trigger a return to the stock from many investors who had abandoned ship.


Other major companies reporting next week include Google , IBM , Johnson & Johnson and DuPont on Tuesday, Microsoft and 3M on Thursday and Procter & Gamble on Friday.


CASH POURING IN, HOUSING DATA COULD HELP


Perhaps the strongest support for equities will come from the flow of cash from fixed income funds to stocks.


The recent piling into stock funds -- $11.3 billion in the past two weeks, the most since 2000 -- indicates a riskier approach to investing from retail investors looking for yield.


"From a yield perspective, a lot of stocks still yield a great deal of money and so it is very easy to see why money is pouring into the stock market," said Stephen Massocca, managing director at Wedbush Morgan in San Francisco.


"You are just not going to see people put a lot of money to work in a 10-year Treasury that yields 1.8 percent."


Housing stocks <.hgx>, already at a 5-1/2 year high, could get a further bump next week as investors eye data expected to support the market's perception that housing is the sluggish U.S. economy's bright spot.


Home resales are expected to have risen 0.6 percent in December, data is expected to show on Tuesday. Pending home sales contracts, which lead actual sales by a month or two, hit a 2-1/2 year high in November.


The new home sales report on Friday is expected to show a 2.1 percent increase.


The federal debt ceiling negotiations, a nagging worry for investors, seemed to be stuck on the back burner after House Republicans signaled they might support a short-term extension.


Equity markets, which tumbled in 2011 after the last round of talks pushed the United States close to a default, seem not to care much this time around.


The CBOE volatility index <.vix>, a gauge of market anxiety, closed Friday at its lowest since April 2007.


"I think the market is getting somewhat desensitized from political drama given, this seems to be happening over and over," said Destination Wealth Management's Yoshikami.


"It's something to keep in mind, but I don't think it's what you want to base your investing decisions on."


(Reporting by Rodrigo Campos, additional reporting by Chuck Mikolajczak and Caroline Valetkevitch; Editing by Kenneth Barry)



Read More..