Syria rebels seize base as envoy holds talks


BEIRUT/GENEVA (Reuters) - Rebels seized control of one of Syria's largest helicopter bases on Friday, opposition sources said, in their first capture of a military airfield used by President Bashar al-Assad's forces.


Fighting raged across the country as international mediator Lakhdar Brahimi sought a political solution to Syria's civil war, meeting senior U.S. and Russian officials in Geneva.


But the two world powers are still deadlocked over Assad's fate in any transition.


The United States, which backs the 21-month-old revolt, says Assad can play no future role, while Syria's main arms supplier Russia said before the talks that his exit should not be a precondition for negotiations.


Syria is mired in bloodshed that has cost more than 60,000 lives and displaced millions of people. Severe winter weather is compounding their misery. The U.N. children's agency UNICEF says more than 2 million children are struggling to stay warm.


The capture of Taftanaz air base, after months of sporadic fighting, could help rebels solidify their hold on northern Syria, according to Rami Abdelrahman, head of the pro-opposition Syrian Observatory for Human Rights.


TACTICAL, NOT STRATEGIC GAIN


But Yezid Sayigh, at the Carnegie Middle East Centre in Beirut, said it was not a game-changer, noting that it had taken months for the rebels to overrun a base whose usefulness to the military was already compromised by the clashes around it.


"This is a tactical rather than a strategic gain," he said.


In Geneva, U.N.-Arab League envoy Brahimi's closed-door talks began with individual meetings with U.S. Deputy Secretary of State William Burns and Russian Deputy Foreign Minister Mikhail Bogdanov. He later held talks with both sides together.


A U.S. official said negotiations would focus on "creating the conditions to advance a political solution - specifically a transitional governing body".


Six months ago, world powers meeting in Geneva proposed a transitional government but left open Assad's role. Brahimi told Reuters on Wednesday that the Syrian leader could play no part in such a transition and suggested it was time he quit.


Responding a day later, Syria's foreign ministry berated the veteran Algerian diplomat as "flagrantly biased toward those who are conspiring against Syria and its people".


Russia has argued that outside powers should not decide who should take part in any transitional government.


"Only the Syrians themselves can agree on a model or the further development of their country," Foreign Ministry spokesman Alexander Lukashevich said.


REFUGEE MISERY


But Syrians seem too divided for any such agreement.


The umbrella opposition group abroad, the Syrian National Coalition, said on Friday it had proposed a transition plan that would kept government institutions intact at a meeting with diplomats in London this week. But the plan has received no public endorsement from the opposition's foreign backers.


With no end to fighting in sight, the misery of Syrian civilians has rapidly increased, especially with the advent of some of the worst winter conditions in years.


Saudi Arabia said it would send $10 million worth of aid to help Syrian refugees in Jordan, where torrential rain has flooded hundreds of tents in the Zaatari refugee camp.


A fierce storm that swept the region has raised concerns for 600,000 Syrian refugees who have fled to neighboring countries, as well as more than 2.5 million displaced inside Syria, many of whom live in flimsy tents at unofficial border camps.


Opposition activists report dozens of weather-related deaths in Syria in the last four days. UNICEF said refugee children are at risk because conditions have hampered access to services.


Earlier this week, another United Nations agency said around one million Syrians were going hungry. The World Food Programme cited difficulties entering conflict zones and said that the few government-approved aid agencies allowed to distribute aid were stretched to the limit.


The WFP said it supplying rations to about 1.5 million people in Syria each month, far short of the 2.5 million deemed to be in need.


(Additional reporting by Alexander Dzsiadosz in Beirut and Raissa Kasolowsky in Abu Dhabi; Editing by Alistair Lyon)



Read More..

Skype founder browses globe for next tech earner






LONDON (Reuters) – Niklas Zennstrom, co-founder of internet phone service Skype, believes the next hot tech business will just as likely spring from Istanbul or Sao Paolo as from Silicon Valley or the coolest districts of London.


And he is prepared to fly around the world to find it.






“Talent can pop up anywhere in the world, it’s not just one city block,” the Swedish entrepreneur and venture capitalist said at the headquarters of his Atomico fund, based on upmarket New Bond Street in central London.


Zennstrom, who retains faint traces of a Swedish accent despite his years of globetrotting, is looking for start-ups ready to shift up a gear into new markets and has the experience, gained from growing Skype into a service used by millions around the world, to help them.


Skype was sold to eBay Inc in 2005 for roughly $ 3 billion, before being bought back by a consortium including Zennstrom in 2009 and then two years later sold on to Microsoft Corp for $ 8.5 billion, leaving him a multi-millionaire.


“If you have a product that works it’s important to scale (up) the business as quickly as possible,” said Zennstrom, named by Time Magazine in 2006 as one of its 100 most influential people. “As entrepreneurs, usually you may not have that experience; how does Asia work? Europe? Latin America?”


Atomico, founded by Zennstrom in 2006, has invested in companies in northern Europe including Finland-based Rovio, developer of Angry Birds, and Hailo, a London-based startup that has developed an app that connects passengers with taxi drivers and has raised $ 20 million so far.


It also led a $ 105 million funding round for U.S. online retailer Fab in July.


FUTURE PORTFOLIO


The investment fund, whose London office reception is decked out with simple designer furniture and modern art pieces, has opened offices in Turkey and Brazil, emerging markets with growing middle classes eager to shop online and buy internet services.


Zennstrom wants to make these markets a large part of Atomico’s portfolio in future.


The firm in 2011 backed Brazilian online retailers such as car parts supplier Connect Parts and announced a $ 16 million investment in a Russian online travel agency in October.


Atomico is not necessarily looking for the latest gizmo or internet trend, but savvy businesses with talented leaders who can take advantage of growth in nascent sectors such as e-commerce.


And Zennstrom, softly spoken and wearing an open-necked shirt and dark jacket, believes emerging market growth is fuelling a new breed of optimism and ambition.


“It’s a much more of an entrepreneurial spirit (in Turkey and Brazil) compared to southern European where it’s a depressed mindset,” he said.


Zennstrom earned his stripes in the tech world after helping launch file-sharing service Kazaa more than a decade ago, which failed as a business but paved the way for Skype.


He said getting investment today was far easier than when he was starting Skype. It took him a year to secure funding, whereas today the most talented entrepreneurs with the best ideas could take their pick of investors.


There is also increasing recognition that entrepreneurs might want to realize some of the value of their creations, something he said was lacking when Skype became successful.


“There was really no IPO market and it was not really accepted for founders to sell some of their shares to get some money off the table,” he said, adding that before Skype was sold to eBay, he could not even secure a mortgage on an apartment.


“I think we made the right decision for the time in terms of selling (Skype),” he said. “Today as an entrepreneur you have more options.”


(Editing by David Holmes)


Internet News Headlines – Yahoo! News





Title Post: Skype founder browses globe for next tech earner
Url Post: http://www.news.fluser.com/skype-founder-browses-globe-for-next-tech-earner/
Link To Post : Skype founder browses globe for next tech earner
Rating:
100%

based on 99998 ratings.
5 user reviews.
Author: Fluser SeoLink
Thanks for visiting the blog, If any criticism and suggestions please leave a comment




Read More..

Survivor: Caramoan - Fans vs. Favorites: See Who's Back















01/11/2013 at 09:00 AM EST







From left: Phillip Sheppard, Malcolm Freberg and Brandon Hantz


CBS/Landov (3)


The 26th season of Survivor will be the ultimate "Redemption Island" for ten returning contestants who will face off against ten newcomers on Survivor: Caramoan – Fans vs. Favorites.

A few of the returning contestants caught up with PEOPLE just before starting their "adventure of a lifetime" ... once again.

Malcolm Freberg, the Frequent Flyer
Less than three weeks after returning from filming Survivor: Philippines, Freberg was headed back out to the wilderness for a second shot at the $1 million dollar prize.

"My mental strategy has been to just not unwind," Freberg told PEOPLE during his short time in the U.S. between seasons. "I'm at the grocery store and someone will ask me a simple question and I'm thinking, 'What does he mean by that?' You don't trust anyone."

Freberg, 25, was a force in challenges and a charismatic player on Philippines, where he placed fourth. But in the Caramoan Islands, he will face off against returning players and fans who will not have had the opportunity to watch his season.

"I'm like the new kid on the block. I'm a wildcard and there is a stigma attached to being the guy that nobody knows anything about," said Freberg, who ate a large amount of sweets and drank plenty of beer while home in hopes of re-gaining the weight he lost while in the Philippines.

Brandon Hantz, the Repentant Liar
While his super-villain uncle Russell Hantz will not be back to play Survivor for a fourth time, Brandon returns to the game with a new mentality after cracking under the pressures of trying to reconcile his faith with strategy on Survivor: South Pacific.

"I was an emotional wreck when I played [the first time]," said Brandon, who placed sixth in 2011. "But now I've done it one time already, which created callouses as far as emotions are concerned. [Before] I didn't know that I didn't have to live a life like a monk. Now I know this game is not going to change my relationship with God."

Brandon, 21, will be reunited with his South Pacific castmates Dawn Meehan and John Cochran, but he does not expect previous relationships to cloud his judgment.

"It's pretty cool to have friends in the cast but to an extent, that goes out the window for me," he said. "Hopefully not for them, though. Hopefully they keep [their friendship with me] intact."

Phillip Sheppard, The Rogue "Agent"
As a contestant on Survivor: Redemption Island, Sheppard became notorious for wearing a feather in his headband, his pink underwear and his abrasive antics that left his tribemates uncomfortable – but the so-called "former federal agent" would not have his competitors see it any other way.

"I will give them a little sample of the Phillip they saw play [on Redemption Island] to make them feel like they can control me," said Sheppard, who made it to the finals alongside Redemption Island winner Rob Mariano in 2011. "But I will be in control. I will win this season."

Sheppard, 54, will be joined by his former Redemption Island tribemates Andrea Boehlke and Francesca Hogi, the only returning player to have been eliminated at the first tribal council.

"It would be funny if Francesca and I could come together and make everybody believe she hates me and I hate her and we ran the season," Sheppard said of possibly teaming up with his former tribemate, whose name he was never able to pronounce correctly. "I don't think it will happen but that would be fun."

Also joining the tribe of Favorites will be Gabon's Corrine Kaplan and Nicaragua's Brenda Lowe, who could team up and convince the final returning player, Micronesia's Erik Reichenbach, to give up his immunity necklace for a second time.

Survivor: Caramoan premieres Feb. 13 on CBS.

Read More..

Flu season strikes early and, in some places, hard


NEW YORK (AP) — From the Rocky Mountains to New England, hospitals are swamped with people with flu symptoms. Some medical centers are turning away visitors or making them wear face masks, and one Pennsylvania hospital set up a tent outside its ER to deal with the feverish patients.


Flu season in the U.S. has struck early and, in many places, hard.


While flu normally doesn't blanket the country until late January or February, it is already widespread in more than 40 states, with about 30 of them reporting some major hot spots. On Thursday, health officials blamed the flu for the deaths of 20 children so far.


Whether this will be considered a bad season by the time it has run its course in the spring remains to be seen.


"Those of us with gray hair have seen worse," said Dr. William Schaffner, a flu expert at Vanderbilt University in Nashville.


The evidence so far points to a moderate season, Schaffner and others say. It looks bad in part because last year was unusually mild and because the main strain of influenza circulating this year tends to make people sicker and really lay them low.


David Smythe of New York City saw it happen to his 50-year-old girlfriend, who has been knocked out for about two weeks. "She's been in bed. She can't even get up," he said.


Also, the flu's early arrival coincided with spikes in a variety of other viruses, including a childhood malady that mimics flu and a new norovirus that causes vomiting and diarrhea, or what is commonly known as "stomach flu." So what people are calling the flu may, in fact, be something else.


"There may be more of an overlap than we normally see," said Dr. Joseph Bresee, who tracks the flu for the Centers for Disease Control and Prevention.


Most people don't undergo lab tests to confirm flu, and the symptoms are so similar that it can be hard to distinguish flu from other viruses, or even a cold. Over the holidays, 250 people were sickened at a Mormon missionary training center in Utah, but the culprit turned out to be a norovirus, not the flu.


Flu is a major contributor, though, to what's going on.


"I'd say 75 percent," said Dr. Dan Surdam, head of the emergency department at Cheyenne Regional Medical Center, Wyoming's largest hospital. The 17-bed emergency room saw its busiest day ever last week, with 166 visitors.


The early onslaught has resulted in a spike in hospitalizations. To deal with the influx and protect other patients from getting sick, hospitals are restricting visits from children, requiring family members to wear masks and banning anyone with flu symptoms from maternity wards.


One hospital in Allentown, Pa., set up a tent this week for a steady stream of patients with flu symptoms. But so far "what we're seeing is a typical flu season," said Terry Burger, director of infection control and prevention for the hospital, Lehigh Valley Hospital-Cedar Crest.


On Wednesday, Boston declared a public health emergency, with the city's hospitals counting about 1,500 emergency room visits since December by people with flu-like symptoms.


All the flu activity has led some to question whether this year's flu shot is working. While health officials are still analyzing the vaccine, early indications are that it's about 60 percent effective, which is in line with what's been seen in other years.


The vaccine is reformulated each year, based on experts' best guess of which strains of the virus will predominate. This year's vaccine is well-matched to what's going around. The government estimates that between a third and half of Americans have gotten the vaccine.


In New York City, 57-year-old Judith Quinones skipped getting a flu shot this season and suffered her worst case of flu-like illness in years. She was laid up for nearly a month with fever and body aches. "I just couldn't function," she said.


But her daughter got the vaccine. "And she got sick twice," Quinones said.


Europe is also suffering an early flu season, though a milder strain predominates there. Flu reports are up, too, in China, Japan, the West Bank, the Gaza Strip, Algeria and the Republic of Congo. Britain has seen a surge in cases of norovirus.


On average, about 24,000 Americans die each flu season, according to the CDC. That's an estimate — the agency does not keep a running tally of adult flu deaths each year, only for children. Some state health departments do keep count, and they've reported dozens of flu deaths so far.


Flu usually peaks in midwinter. Symptoms can include fever, cough, runny nose, head and body aches and fatigue. Some people also suffer vomiting and diarrhea, and some develop pneumonia or other severe complications.


Most people with flu have a mild illness and can help themselves and protect others by staying home and resting. But people with severe symptoms should see a doctor. They may be given antiviral drugs or other medications to ease symptoms.


Flu vaccinations are recommended for everyone 6 months or older. Of the 20 children killed by the flu this season, only two were fully vaccinated.


___


AP Medical Writer Maria Cheng in London contributed to this report.


___


Online:


CDC flu: http://www.cdc.gov/flu/index.htm


Read More..

Wall Street to open firm after Thursday's gains, Wells Fargo results


NEW YORK (Reuters) - Stocks were set to firm at the open on Friday after the S&P 500 climbed to a five-year high a day earlier, as record profit from Wells Fargo failed to excite investors who awaited fresh trading incentives.


"The bigger news lies ahead of us in terms of earnings and also reports on Christmas sales, which seem to be poor so far," said Rick Meckler, president of investment firm LibertyView Capital Management in Jersey City, New Jersey.


Wells Fargo , the first major U.S. bank to post earnings this season, reported a higher fourth-quarter profit as it set aside less money to cover bad loans and made more fees from mortgages. While shares dropped 1.1 percent to $35 in premarket trading, the stock had climbed 2 percent Thursday ahead of the results, and is up 3.6 percent this month so far.


Best Buy shares were volatile in premarket trading after it reported flat holiday sales at established U.S. stores. Shares were last up 5.7 percent at $12.91.


Basic materials shares could be pressured after China's annual consumer inflation rate picked up to a seven-month high, narrowing the scope for the central bank to boost the economy by easing monetary policy.


Meckler said that in the absence of major news, the market will continue to absorb some of the money that comes in from institutional investors at the start of the year. This could give equities an upside bias.


S&P 500 futures were flat and were slightly above fair value, a formula that evaluates pricing by taking into account interest rates, dividends and time to expiration on the contract. Dow Jones industrial average futures added 3 points and Nasdaq 100 futures rose 2 points.


American Express said it would take a $600-million quarterly charge relating to 5,400 job cuts and payment of legal bills, a move likely to halve its net income. Its shares dipped 0.5 percent in premarket trading to $60.51.


Boeing's 787 Dreamliner jet was dogged by further incidents that tested confidence in the new plane. It suffered a cracked cockpit window and an oil leak on separate flights in Japan on Friday. The US Department of Transportation said the jet would be subject to a review of its critical systems by regulators. Boeing shares fell 1.5 percent to $75.90 in premarket trading.


Dendreon Corp shares jumped 14.9 percent to $5.86 after Sanford C. Bernstein upgraded the stock to "outperform" from "market-perform" and said the drugmaker could be one of the best performers in 2013.


U.S.-traded shares of India's No.2 software services provider Infosys Ltd jumped 15.2 percent premarket after the company raised its revenue forecast.


In a move that could support US equities and boost the global economic outlook, the Japanese government approved a massive $117 billion of spending to revive the world's third-largest economy in the biggest stimulus plan since the financial crisis.


(Editing by Bernadette Baum)



Read More..

NATO official says more missiles launched in Syria


BRUSSELS (Reuters) - A short-range ballistic missile was fired inside Syria on Wednesday, following similar launches last week, a NATO official said on Thursday.


The official condemned as "reckless" the missile launches, which U.S. officials called an escalation of the 21-month-old Syrian civil war when their use was first spotted last month.


"The use of such indiscriminate weapons shows utter disregard for the lives of the Syrian people," he said.


The official said NATO had detected the launch of an unguided, short-range ballistic missile inside Syria on Wednesday, following similar launches on January 2 and 3. All the missiles were fired from inside Syria and landed in northern Syria, he said.


The description of the missiles fits the Scuds that are in the Syrian military's armory, but the official said NATO could not confirm the type of missile used.


The NATO official was responding to a report from a Syrian opposition activist living near the Qaldoun army base, 50 km (30 miles) north of Damascus, who said four large rockets, apparently Scuds, were fired from the base overnight.


NATO has agreed to send Patriot anti-missile batteries to protect its member Turkey from possible missile attack from Syria.


(Reporting by Adrian Croft; editing by Rex Merrifield and Sebastian Moffett)



Read More..

Netflix announces ‘Super HD’ and 3D streaming for select ISPs






Netflix (NFLX) on Tuesday announced new enhanced streaming options for users on select ISPs. Following a series of rumors that suggested as much, Netflix has confirmed the availability of “Super HD” streaming — which is simply Netflix’s branding for 1080p content — and 3D video streaming. Both services are available immediately with a huge caveat: only Netflix subscribers with Cablevision or Google Fiber Internet service have access to the new content. For those lucky subscribers, Super HD and 3D content is accessible using a number of devices including the Wii U, compatible Roku players, the Apple TV, Windows 8 PCs and select smart TVs and Blu-ray players. Netflix’s full press release follows below.



Netflix “Open Connect” Delivery Network Gains Widespread Global Acceptance
Cablevision Most Recent Major Provider to Join Open Connect
New Super HD and 3D Video Formats Available on Open Connect






[More from BGR: Apple’s next iPhone to reportedly feature larger screen and ‘brand new exterior design’]


Jan 8, 2013


LAS VEGAS, Jan. 8, 2013 /PRNewswire/ — Netflix Open Connect, the single purpose video content delivery network launched last year, is now delivering the majority of Netflix international traffic and is growing at a rapid pace in the domestic market.


In early 2012 Netflix began enabling Internet service providers (ISPs) to receive, at no cost to them, Netflix video directly at the interconnection point of the ISP’s choice. By connecting directly through Open Connect, ISPs can more effectively manage their networks and more efficiently deliver Internet services to consumers, including the more than 1 billion hours of Netflix TV shows and movies consumers watch every month.


Netflix Open Connect is now widely deployed around the world, serving the vast majority of Netflix video in Europe, Canada and Latin America, and a growing proportion in the U.S., where Netflix has over 25 million streaming members.


“Leading-edge ISPs around the world such as Cablevision, Virgin Media, British Telecom, Telmex, Telus, TDC, GVT, among many others, are already participating in Open Connect to provide the highest-possible quality Netflix service to consumers,” said Netflix Chief Executive Officer Reed Hastings. “Our goal is to have all of our members served by Open Connect as soon as possible.”


“Optimum is committed to providing the highest-quality TV, phone and Internet to our customers, and our new partnership with Netflix supports this critical objective,” said James L. Dolan, president and CEO of Cablevision, the most recent major provider to join Open Connect. “With Open Connect, we are establishing a direct local connection with Netflix that delivers a higher-quality Netflix viewing experience for Optimum customers than Verizon or AT&T can provide, including access to new Netflix Super HD and 3D TV shows and movies.”


Netflix Super HD and 3D


Now available through Open Connect partners, Netflix Super HD is the highest quality video format offered by Netflix, providing an even better picture on 1080p HDTVs.


In the U.S., Netflix is also for the first time offering a small number of titles streaming in 3D through Open Connect partners. Available for 3D viewing are, among other titles, the action fantasy drama “Immortals,” Red Bull Media House’s snowboarding documentary “The Art of Flight,” and a number of titles from the Discovery/Sony/Imax joint venture 3net Studios – including the native, original 3D series “African Wild,” “Scary Tales,” and “Live Fire.” Depending on member demand, Netflix will consider adding 3D titles and expanding availability to international markets.


“These new Super HD and 3D formats are more challenging to deliver than our other video streams, which is why we will deliver them through Open Connect,” said Ken Florance, vice president of content delivery at Netflix. “Any ISP that wants to be able to deliver our new formats can do so easily and for free.”


Netflix members can verify if their ISP is part of Open Connect and provides access to Netflix Super HD and, in the U.S. only, 3D on this Web site: http://www.netflix.com/superhd


ISPs that are not yet on Open Connect can contact Netflix at openconnect.netflix.com to start their Open Connect relationship. As part of Open Connect, Netflix is also sharing its hardware design and the open source software components. These designs are suitable for any other provider of large media files and are very cost efficient.



Linux/Open Source News Headlines – Yahoo! News





Title Post: Netflix announces ‘Super HD’ and 3D streaming for select ISPs
Url Post: http://www.news.fluser.com/netflix-announces-super-hd-and-3d-streaming-for-select-isps/
Link To Post : Netflix announces ‘Super HD’ and 3D streaming for select ISPs
Rating:
100%

based on 99998 ratings.
5 user reviews.
Author: Fluser SeoLink
Thanks for visiting the blog, If any criticism and suggestions please leave a comment




Read More..

It's a Girl for Lily Allen




Celebrity Baby Blog





01/10/2013 at 08:30 AM ET



Lily Allen Welcomes Daughter Marnie Rose
PA Photos/Landov


Cue the lullabies: Lily Allen is a mom — again!


The “Smile” singer and her husband Sam Cooper welcomed her second daughter — and the baby girl shares her special day with rock legends Elvis and David Bowie. Marnie Rose arrived on Tuesday, Jan. 8, according to reports.


The couple — who wed in Gloucestershire, England in June 2011 — are already parents to 13-month-old daughter Ethel Mary.


Her rep declined to confirm the pregnancy in July, but after stepping out several times with a burgeoning belly, no official confirmation was needed when 27-year-old Allen appeared radiant on the red carpet during the British Fashion Awards in November.

On New Year’s Eve, Allen was anxious the tot would emerge soon, Tweeting she was “only planning on spending a few days of [2013] pregnant. Unlike the last 3 years.” And she said she had been sampling curries to try to force labor.


A rep for the singer (who goes by her married name Cooper) didn’t immediately respond to requests for comment or statement, but Allen appeared to acknowledge the news Thursday when she thanked fans, writing, “Quite overwhelmed by all the well wishing going on. THANKYOU everybody x x x”


One of those came from actor friend Charlie Condou, who Tweeted he had a “little cry” when Lily “told me Marnie Rose was born” on his birthday.


– Anya Leon and Simon Perry


Read More..

Retooling Pap test to spot more kinds of cancer


WASHINGTON (AP) — For years, doctors have lamented that there's no Pap test for deadly ovarian cancer. Wednesday, scientists reported encouraging signs that one day, there might be.


Researchers are trying to retool the Pap, a test for cervical cancer that millions of women get, so that it could spot early signs of other gynecologic cancers, too.


How? It turns out that cells can flake off of tumors in the ovaries or the lining of the uterus, and float down to rest in the cervix, where Pap tests are performed. These cells are too rare to recognize under the microscope. But researchers from Johns Hopkins University used some sophisticated DNA testing on the Pap samples to uncover the evidence — gene mutations that show cancer is present.


In a pilot study, they analyzed Pap smears from 46 women who already were diagnosed with either ovarian or endometrial cancer. The new technique found all the endometrial cancers and 41 percent of the ovarian tumors, the team reported Wednesday in the journal Science Translational Medicine.


This is very early-stage research, and women shouldn't expect any change in their routine Paps. It will take years of additional testing to prove if the so-called PapGene technique really could work as a screening tool, used to spot cancer in women who thought they were healthy.


"Now the hard work begins," said Hopkins oncologist Dr. Luis Diaz, whose team is collecting hundreds of additional Pap samples for more study and is exploring ways to enhance the detection of ovarian cancer.


But if it ultimately pans out, "the neat part about this is, the patient won't feel anything different," and the Pap wouldn't be performed differently, Diaz added. The extra work would come in a lab.


The gene-based technique marks a new approach toward cancer screening, and specialists are watching closely.


"This is very encouraging, and it shows great potential," said American Cancer Society genetics expert Michael Melner.


"We are a long way from being able to see any impact on our patients," cautioned Dr. Shannon Westin of the University of Texas MD Anderson Cancer Center. She reviewed the research in an accompanying editorial, and said the ovarian cancer detection would need improvement if the test is to work.


But she noted that ovarian cancer has poor survival rates because it's rarely caught early. "If this screening test could identify ovarian cancer at an early stage, there would be a profound impact on patient outcomes and mortality," Westin said.


More than 22,000 U.S. women are diagnosed with ovarian cancer each year, and more than 15,000 die. Symptoms such as pain and bloating seldom are obvious until the cancer is more advanced, and numerous attempts at screening tests have failed.


Endometrial cancer affects about 47,000 women a year, and kills about 8,000. There is no screening test for it either, but most women are diagnosed early because of postmenopausal bleeding.


The Hopkins research piggybacks on one of the most successful cancer screening tools, the Pap, and a newer technology used along with it. With a standard Pap, a little brush scrapes off cells from the cervix, which are stored in a vial to examine for signs of cervical cancer. Today, many women's Paps undergo an additional DNA-based test to see if they harbor the HPV virus, which can spur cervical cancer.


So the Hopkins team, funded largely by cancer advocacy groups, decided to look for DNA evidence of other gynecologic tumors. It developed a method to rapidly screen the Pap samples for those mutations using standard genetics equipment that Diaz said wouldn't add much to the cost of a Pap-plus-HPV test. He said the technique could detect both early-stage and more advanced tumors. Importantly, tests of Paps from 14 healthy women turned up no false alarms.


The endometrial cancers may have been easier to find because cells from those tumors don't have as far to travel as ovarian cancer cells, Diaz said. Researchers will study whether inserting the Pap brush deeper, testing during different times of the menstrual cycle, or other factors might improve detection of ovarian cancer.


Read More..

Wall Street climbs at open on China data


NEW YORK (Reuters) - Stocks advanced at the open on Thursday as stronger-than-expected exports in China, the world's second-biggest economy, raised hopes for a more robust recovery in the global economy this year.


The Dow Jones industrial average <.dji> gained 51.22 points, or 0.38 percent, to 13,441.73. The Standard & Poor's 500 Index <.spx> climbed 8.01 points, or 0.55 percent, to 1,469.03. The Nasdaq Composite Index <.ixic> rose 21.80 points, or 0.70 percent, to 3,127.61.


(Reporting by Chuck Mikolajczak; Editing by Bernadette Baum)



Read More..